Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715967 | 1.00 | HDAC1 (0.50) | HDAC1HDAC6SMN1; SMN2MAPTTP53 | |
| SCHEMBL29670989 | 0.92 | HDAC1 (0.50) | HDAC1HDAC6SMN1; SMN2MAPTTP53 | |
| SCHEMBL28705611 | 0.92 | HDAC1 (0.50) | HDAC1HDAC6SMN1; SMN2MAPTTP53 | |
| SCHEMBL28707697 | 0.88 | FAAH (0.49) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL28707698 | 0.83 | MAPT (0.54) | SMN1; SMN2MAPTTP53ALDH1A1MEN1 | |
| SCHEMBL28703410 | 0.79 | CYP2C9 (0.58) | HDAC1HDAC6SMN1; SMN2MAPTTP53 | |
| SCHEMBL28718272 | 0.79 | ACHE (0.48) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL28715966 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2MAPTTP53ALDH1A1HSD17B10 | |
| SCHEMBL29670962 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23754421 | 0.73 | ACHE (0.57) | HDAC1HDAC6SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |