Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876511 | 0.89 | AKT1 (0.35) | SNCA | |
| SCHEMBL2876778 | 0.87 | AKT1 (0.41) | ECE1 | |
| SCHEMBL2874795 | 0.83 | ECE1 (0.43) | SNCAECE1 | |
| SCHEMBL2874609 | 0.83 | ECE1 (0.43) | SNCAECE1 | |
| SCHEMBL2876221 | 0.80 | AKT1 (0.43) | — | |
| SCHEMBL2876171 | 0.74 | CDC42BPB (0.41) | — | |
| SCHEMBL2876524 | 0.73 | ROCK1 (0.36) | — | |
| SCHEMBL2876595 | 0.72 | CDC42BPB (0.34) | — | |
| SCHEMBL2874191 | 0.72 | AKT1 (0.38) | SNCA | |
| SCHEMBL2874136 | 0.72 | AKT1 (0.37) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2002836-B1 | Cyclocondensed azaindoles active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL (IT) | 2010-10-20 | — | — | EP | claimed |
| EP-2002836-A1 | Cyclocondensed azaindoles active as kinase inhibitors | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-17 | — | — | EP | claimed |
| EP-2002836-B1 | Cyclocondensed azaindoles active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL (IT) | 2010-10-20 | — | — | EP | disclosed |
| EP-2002836-A1 | Cyclocondensed azaindoles active as kinase inhibitors | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-17 | — | — | EP | disclosed |