Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215923 | 1.00 | TPMT (0.51) | TPMTPKMLMNAHTTPOLB | |
| Potassium Ion SCHEMBL2681690 | 0.98 | TPMT (0.50) | TPMTPKMLMNAHTTPOLB | |
| SCHEMBL2681686 | 0.98 | TPMT (0.50) | TPMTPKMLMNAHTTPOLB | |
| SCHEMBL3698713 | 0.97 | PKM (0.52) | TPMTPKMLMNAHTTPOLB | |
| SCHEMBL16945800 | 0.94 | PKM (0.55) | TPMTPKMLMNAHTTPOLB | |
| SCHEMBL28708249 | 0.93 | POLB (0.46) | TPMTPKMLMNAHTTPOLB | |
| SCHEMBL31549975 | 0.88 | PKM (0.59) | PKMLMNAHTTPOLBCYP3A4 | |
| SCHEMBL375897 | 0.88 | PKM (0.59) | PKMLMNAHTTPOLBCYP3A4 | |
| Methyl Alcohol SCHEMBL27781670 | 0.87 | PKM (0.58) | PKMLMNAHTTPOLBCYP3A4 | |
| Potassium Ion SCHEMBL2681688 | 0.86 | LMNA (0.47) | TPMTPKMLMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962908-A1 | HETEROCYCLIC INHIBITORS OF TYROSINE KINASE | Board of Regents, The University of Texas System (US) | 2022-03-09 | — | — | EP | disclosed |