Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696633 | 0.83 | MGLL (0.51) | MGLLALDH1A1TDP1 | |
| SCHEMBL28714863 | 0.81 | MGLL (0.69) | MGLL | |
| SCHEMBL20137015 | 0.77 | MGLL (0.69) | MGLLCHRM3 | |
| SCHEMBL28699391 | 0.71 | ALDH1A1 (0.44) | MGLLALDH1A1TDP1MLNRPOLB | |
| SCHEMBL20137036 | 0.68 | MGLL (0.68) | MGLL | |
| SCHEMBL20137140 | 0.67 | MGLL (0.67) | MGLL | |
| SCHEMBL20167062 | 0.64 | MGLL (0.63) | MGLLALDH1A1POLBKDM4E | |
| SCHEMBL21883706 | 0.63 | MGLL (0.36) | MGLLALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28086944 | 0.62 | SLC6A4 (0.43) | ALDH1A1TDP1MLNRKDM4ECHRM3 | |
| SCHEMBL28887675 | 0.60 | DDR1 (0.42) | MGLLALDH1A1TDP1MLNRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267963-B | MAGL inhibitors | H.隆德贝克有限公司 | 2022-04-01 | — | — | CN | disclosed |