Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714952 | 0.82 | L3MBTL1 (0.36) | L3MBTL1HTTCYP1A2CYP2C19AMY1A | |
| SCHEMBL25254145 | 0.71 | CHEK1 (0.39) | L3MBTL1HTTCYP1A2CYP2C19F2 | |
| SCHEMBL28718890 | 0.70 | PIK3CD (0.43) | CYP1A2CYP2C19LMNACYP19A1METAP2 | |
| SCHEMBL29472077 | 0.68 | L3MBTL1 (0.39) | KEAP1NFE2L2L3MBTL1HTTLMNA | |
| SCHEMBL22715562 | 0.68 | L3MBTL1 (0.39) | KEAP1NFE2L2L3MBTL1HTTLMNA | |
| SCHEMBL28705738 | 0.68 | LMNA (0.50) | KEAP1NFE2L2CYP1A2LMNAPKM | |
| SCHEMBL22347246 | 0.68 | KEAP1 (0.46) | KEAP1NFE2L2L3MBTL1AMY1ALMNA | |
| SCHEMBL29524637 | 0.67 | MEN1 (0.61) | L3MBTL1HTTCYP1A2CYP2C19LMNA | |
| SCHEMBL25425966 | 0.67 | MEN1 (0.61) | L3MBTL1HTTCYP1A2CYP2C19LMNA | |
| SCHEMBL3279666 | 0.66 | CHEK1 (0.47) | HTTCYP1A2CYP2C19F2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |