Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936445 | 0.71 | PPARG (0.43) | PPARGPPARAEPHX2LMNACYP1A2 | |
| SCHEMBL3643384 | 0.67 | PPARG (0.41) | PPARGPPARAEPHX2LMNACYP3A4 | |
| SCHEMBL28966364 | 0.64 | EPHX1 (0.42) | PPARGPPARALMNACYP2C9NFKB1 | |
| SCHEMBL1934151 | 0.64 | EPHX1 (0.42) | PPARGPPARALMNACYP2C9NFKB1 | |
| SCHEMBL1934595 | 0.64 | KMT2A (0.44) | PPARGPPARALMNASMN1; SMN2 | |
| SCHEMBL16569006 | 0.63 | PPARG (0.44) | PPARGPPARAEPHX2LMNACYP3A4 | |
| SCHEMBL8139642 | 0.63 | EPHX1 (0.43) | PPARGPPARAF2EPHX1KIF11 | |
| SCHEMBL1526008 | 0.62 | EPHX1 (0.70) | LMNACYP2C9NFKB1SMN1; SMN2PMP22 | |
| SCHEMBL1936079 | 0.62 | LMNA (0.55) | LMNAHSD17B10CYP3A4SMN1; SMN2 | |
| SCHEMBL23533687 | 0.61 | F2 (0.43) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114191428-A | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2022-03-18 | — | — | CN | disclosed |