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SCHEMBL1000520

SCHEMBL1000520

O=P(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.50
▸ CYP2A6 P11509 1/20 0.50
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ CYP1A2 P05177 1/20 0.41
▸ MAPK1 P28482 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ CES2 O00748 1/20 0.39
▸ CES1 P23141 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ IDO1 P14902 1/20 0.38
▸ MMP2 P08253 1/20 0.38
▸ MMP8 P22894 1/20 0.38
▸ MMP14 P50281 1/20 0.38
▸ TSHR P16473 3/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2870880 0.89 CYP1A2 (0.52) LMNACYP2A6MEN1KMT2ACYP1A2
SCHEMBL10522698 0.89 CYP1A2 (0.52) LMNACYP2A6MEN1KMT2ACYP1A2
SCHEMBL18780700 0.82 CYP1A2 (0.50) MEN1KMT2ACYP1A2AHR
SCHEMBL918686 0.79 LMNA (0.47) LMNACYP2A6MEN1KMT2ACYP1A2
SCHEMBL10340793 0.79 LMNA (0.47) LMNACYP2A6MEN1KMT2ACYP1A2
SCHEMBL10523794 0.78 TSHR (0.42) LMNAMEN1KMT2ACYP1A2ALDH1A1
SCHEMBL25146402 0.77 LMNA (0.44) LMNACYP2A6MEN1KMT2ACYP1A2
SCHEMBL11795326 0.77 LMNA (0.44) LMNACYP2A6MEN1KMT2AMAPK1
SCHEMBL3398367 0.77 LMNA (0.44) LMNACYP2A6MEN1KMT2AMAPK1
SCHEMBL10425734 0.77 MEN1 (0.50) LMNACYP2A6MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10815258-B2 Phosphine oxides reduction RHODIA OPERATIONS (FR) 2020-10-27 — — US claimed
US-20200231613-A1 PHOSPHINE OXIDES REDUCTION SPECIALTY OPERATIONS FRANCE (FR) 2020-07-23 — — US claimed
US-7262265-B1 High temperature thermoset compositions SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-08-28 — — US claimed
EP-1366815-B1 Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it TOSOH CORP (JP) 2005-12-28 — — EP claimed
US-20040116721-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it TOSOH CORPORATION (JP) 2004-06-17 — — US claimed
EP-1366815-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it Tosoh Corporation (JP) 2003-12-03 — — EP claimed
US-20010051737-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it TOSOH CORPORATION (JP) 2001-12-13 — — US claimed
EP-1127616-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it Tosoh Corporation (JP) 2001-08-29 — — EP claimed
US-4255324-A A PHOSPHINE OXIDE AND A TRIMETHYLENE PHOSPHONATE; BLENDS WITH POLYSTYRENE, MOLDING MATERIALS AMERICAN CYANAMID COMPANY (US) 1981-03-10 — — US claimed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 — — US claimed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 — — EP disclosed
CN-119968094-A Hole transport composition, hole transport layer, preparation method of hole transport layer and perovskite battery 天合光能股份有限公司 2025-05-09 — — CN disclosed
US-20250066586-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2025-02-27 — — US disclosed
WO-2025041769-A1 POLYCARBONATE RESIN COMPOSITION 三菱エンジニアリングプラスチックス株式会社 2025-02-27 — — WO disclosed
CN-119285673-A Organic phosphine oxide compound, green synthesis method thereof and application of organic phosphine oxide compound in blue light OLED device 中国科学院福建物质结构研究所 2025-01-10 — — CN disclosed
US-4190724-A Process for 3-exomethylenecepham sulfoxides ELI LILLY AND COMPANY (US) 1980-02-26 — — US disclosed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 — — US disclosed
US-4101655-A Insecticidal and ovicidal method M & T CHEMICALS INC. (US) 1978-07-18 — — US disclosed
US-3989824-A MITICIDES M & T CHEMICALS INC. (US) 1976-11-02 — — US disclosed
US-3952045-A FROM AN ALCOHOL AND CARBON MONOXIDE, COPPER, HALIDE, ORGANO-PHOSPHORUS CATALYST ROHM GMBH (DT) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815258-B2 Phosphine oxides reduction PHOSPHO1, PSPH, PTEN LMNA 4532/4885CYP2A6 3562/4885MEN1 161/4885
US-20010051737-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it SQLE, ENO1, GPX4 LMNA 1757/4885CYP2A6 393/4885MEN1 3111/4885
US-20200231613-A1 PHOSPHINE OXIDES REDUCTION PHOSPHO1, PSPH, PTEN LMNA 4532/4885CYP2A6 3562/4885MEN1 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.