Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855165 | 0.88 | MAPT (0.71) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL29633530 | 0.82 | MAPT (1.00) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL701961 | 0.82 | MAPT (1.00) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL26021326 | 0.81 | MAPT (0.65) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9540402 | 0.80 | L3MBTL1 (0.67) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL18066378 | 0.78 | PTPN1 (0.76) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL21436903 | 0.78 | L3MBTL1 (0.58) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL12231213 | 0.78 | MAPT (0.60) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9679320 | 0.78 | MAPT (0.60) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL29466867 | 0.78 | MAOB (0.68) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |