Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.56 |
| ▸ | MMP2 | P08253 | 11/20 | 0.56 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033737 | 0.80 | MMP9 (0.57) | MMP9MMP2MMP13MMP3CA12 | |
| SCHEMBL9570487 | 0.79 | MMP2 (0.52) | MMP9MMP2MMP13MMP3CA2 | |
| SCHEMBL8936409 | 0.77 | MMP2 (0.51) | MMP9MMP2MMP13MMP3CA12 | |
| SCHEMBL10420827 | 0.77 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL10420120 | 0.77 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL10420675 | 0.77 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL7825144 | 0.77 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL10419177 | 0.77 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL29144732 | 0.76 | MMP9 (0.52) | MMP9MMP2MMP13MMP3CA12 | |
| SCHEMBL28043061 | 0.76 | MMP2 (0.52) | MMP9MMP2MMP13MMP3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715637-B | Glucokinase activators and methods of use thereof | 百时美施贵宝公司 | 2022-04-05 | — | — | CN | disclosed |