Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027674 | 0.99 | PARK7 (0.63) | PARK7ALDH1A1ALDH2ALDH3A1CES1 | |
| SCHEMBL17274922 | 0.90 | PARK7 (0.69) | PARK7ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3009244 | 0.89 | ALDH1A1 (0.61) | PARK7ALDH1A1ALDH2ALDH3A1CES1 | |
| SCHEMBL3027497 | 0.88 | CES1 (0.62) | PARK7ALDH1A1ALDH2ALDH3A1CES1 | |
| SCHEMBL29011249 | 0.88 | PARK7 (0.63) | PARK7ALDH1A1ALDH2ALDH3A1MAPT | |
| SCHEMBL29011244 | 0.86 | PARK7 (0.62) | PARK7ALDH1A1CES1CDC25AMAPT | |
| SCHEMBL29011262 | 0.86 | PARK7 (0.64) | PARK7ALDH1A1CES1MAPTKMT2A | |
| SCHEMBL11150416 | 0.86 | PARK7 (0.64) | PARK7ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3027019 | 0.84 | ALDH1A1 (0.55) | PARK7ALDH1A1ALDH2ALDH3A1CES1 | |
| SCHEMBL6559542 | 0.84 | PARK7 (0.64) | PARK7ALDH1A1ALDH3A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456249-B | Synthetic method of isatin derivative | 西北师范大学 | 2022-03-08 | — | — | CN | disclosed |