Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386859 | 0.79 | DRD2 (0.55) | SLC18A3OPRM1ALDH1A1POLBKCNH2 | |
| SCHEMBL21770833 | 0.77 | SLC18A3 (0.58) | SLC18A3OPRM1KCNH2HRH3KMT2A | |
| SCHEMBL24029313 | 0.76 | OPRM1 (0.47) | SLC18A3OPRM1ALDH1A1POLBKCNH2 | |
| SCHEMBL12609029 | 0.75 | HRH3 (0.56) | SLC18A3OPRM1KCNH2HRH3CCR5 | |
| SCHEMBL12609017 | 0.75 | HRH3 (0.56) | SLC18A3OPRM1KCNH2HRH3CCR5 | |
| SCHEMBL2603285 | 0.75 | HRH3 (0.56) | SLC18A3OPRM1KCNH2HRH3CCR5 | |
| SCHEMBL22435855 | 0.74 | ATM (0.49) | NPC1RAB9ASMN1; SMN2MAPTSTAT1 | |
| SCHEMBL24029315 | 0.74 | OPRM1 (0.46) | OPRM1ALDH1A1POLBKCNH2HRH3 | |
| SCHEMBL24112381 | 0.73 | NPC1 (0.50) | OPRM1ALDH1A1POLBKCNH2HRH3 | |
| SCHEMBL662173 | 0.73 | LMNA (0.49) | SLC18A3ALDH1A1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269431-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |