Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425677 | 1.00 | KMT2A (0.48) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL28711495 | 0.85 | KMT2A (0.49) | KMT2AMEN1ACHECYP19A1LMNA | |
| SCHEMBL29425662 | 0.85 | KMT2A (0.49) | KMT2AMEN1ACHECYP19A1LMNA | |
| SCHEMBL28700875 | 0.80 | CYP1A2 (0.47) | LMNANPC1SMN1; SMN2 | |
| SCHEMBL28713377 | 0.78 | ALDH1A1 (0.47) | KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28719786 | 0.78 | CASP3 (0.42) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29425667 | 0.77 | HDAC1 (0.43) | — | |
| SCHEMBL28709464 | 0.77 | HDAC1 (0.43) | — | |
| SCHEMBL28715740 | 0.75 | ALDH1A1 (0.45) | KMT2AMEN1NPC1HTTSMN1; SMN2 | |
| SCHEMBL6202582 | 0.74 | ACHE (0.59) | KMT2AMEN1ACHELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213307-A | Preparation method of N-alkyl substituted pyrrolidone compound | 河南农业大学 | 2022-03-22 | — | — | CN | disclosed |