Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533661 | 0.82 | EGLN1 (0.44) | EGLN1HTR6DCTPP1YTHDC1CYP11B1 | |
| SCHEMBL29424716 | 0.82 | AHCY (0.52) | L3MBTL1MEN1KMT2AEGLN1HTR6 | |
| SCHEMBL29424691 | 0.82 | EGLN1 (0.42) | L3MBTL1MEN1KMT2AEGLN1HTR6 | |
| SCHEMBL22533675 | 0.82 | EGLN1 (0.42) | L3MBTL1MEN1KMT2AEGLN1HTR6 | |
| SCHEMBL22533673 | 0.82 | AHCY (0.52) | L3MBTL1MEN1KMT2AEGLN1HTR6 | |
| SCHEMBL29424873 | 0.82 | EGLN1 (0.44) | EGLN1HTR6DCTPP1YTHDC1CYP11B1 | |
| SCHEMBL22533644 | 0.80 | ACACB (0.39) | HTR6LMNADCTPP1SMN1; SMN2 | |
| SCHEMBL29424845 | 0.80 | ACACB (0.39) | HTR6LMNADCTPP1SMN1; SMN2 | |
| SCHEMBL22533918 | 0.80 | LMNA (0.42) | L3MBTL1MEN1KMT2ALMNAYTHDC1 | |
| SCHEMBL22533420 | 0.80 | HPGD (0.56) | MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | disclosed |