Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 4/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533661 | 1.00 | EGLN1 (0.44) | EGLN1HTR6CYP11B1CYP11B2MAPK1 | |
| SCHEMBL22533673 | 0.86 | AHCY (0.52) | EGLN1HTR6AHCY | |
| SCHEMBL29424716 | 0.86 | AHCY (0.52) | EGLN1HTR6AHCY | |
| SCHEMBL29424691 | 0.86 | EGLN1 (0.42) | EGLN1HTR6CYP11B1CYP11B2MAPK1 | |
| SCHEMBL22533675 | 0.86 | EGLN1 (0.42) | EGLN1HTR6CYP11B1CYP11B2MAPK1 | |
| SCHEMBL28717002 | 0.82 | L3MBTL1 (0.41) | EGLN1HTR6CYP11B1CYP11B2HTT | |
| SCHEMBL8669239 | 0.81 | HTR6 (0.59) | EGLN1HTR6CYP11B1CYP11B2MAPK1 | |
| SCHEMBL22533905 | 0.81 | EGLN1 (0.51) | EGLN1HTR6HDAC6AHCYYTHDC1 | |
| SCHEMBL29424721 | 0.81 | EGLN1 (0.51) | EGLN1HTR6HDAC6AHCYYTHDC1 | |
| SCHEMBL22533568 | 0.81 | CYP11B1 (0.44) | EGLN1HTR6CYP11B1CYP11B2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | disclosed |