Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187600 | 0.74 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL20203363 | 0.71 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL21363618 | 0.71 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL20203396 | 0.69 | TRPA1 (0.81) | TRPA1 | |
| SCHEMBL29434778 | 0.69 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187446 | 0.68 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL28720030 | 0.68 | TRPA1 (0.59) | TRPA1 | |
| SCHEMBL20203315 | 0.67 | TRPA1 (0.45) | TRPA1 | |
| SCHEMBL20203176 | 0.66 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL20187528 | 0.66 | TRPA1 (1.00) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225911-B | Oxadiazolone transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-05 | — | — | CN | disclosed |