SCHEMBL28720579

SCHEMBL28720579

COc1cnc(S(N)(=O)=O)nc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
CA2 P00918 11/20 0.42
CA1 P00915 5/20 0.42
CA9 Q16790 4/20 0.42
PTGS2 P35354 3/20 0.39
CA12 O43570 2/20 0.39
APLNR P35414 2/20 0.37
PKM P14618 1/20 0.35
CA4 P22748 1/20 0.35
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4059831 0.80 SMN1; SMN2 (0.47) LMNACA2CA1CA9PTGS2
SCHEMBL5108030 0.78 LMNA (0.40) LMNACA2CA1CA9APLNR
SCHEMBL23026144 0.74 LMNA (0.47) LMNACA2CA1CA9PTGS2
SCHEMBL28062563 0.72 LMNA (0.61) LMNAPKM
SCHEMBL19551039 0.70 APLNR (0.67) LMNAAPLNR
SCHEMBL20549112 0.70 APLNR (0.67) LMNAAPLNR
SCHEMBL18247273 0.70 APLNR (0.67) LMNAAPLNR
SCHEMBL22851268 0.70 CA1 (0.38) CA2CA1CA9CA12CA4
SCHEMBL4429463 0.69
SCHEMBL504264 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058624-A Aptamer, sensor, kit and application for detecting sulfamoyl-5-methoxypyrimidine 重庆师范大学 2022-02-18 CN claimed
CN-114058624-A Aptamer, sensor, kit and application for detecting sulfamoyl-5-methoxypyrimidine 重庆师范大学 2022-02-18 CN disclosed
CN-114058624-A Aptamer, sensor, kit and application for detecting sulfamoyl-5-methoxypyrimidine 重庆师范大学 2022-02-18 CN disclosed
CN-114058624-A Aptamer, sensor, kit and application for detecting sulfamoyl-5-methoxypyrimidine 重庆师范大学 2022-02-18 CN disclosed