SCHEMBL28062563

SCHEMBL28062563

COc1cnc(S(=O)(=O)c2ccc(N)cc2)nc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
PKM P14618 3/20 0.48
HTR6 P50406 4/20 0.48
CYP3A4 P08684 2/20 0.48
MPO P05164 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 1/20 0.48
ADORA3 P0DMS8 1/20 0.45
SLC6A3 Q01959 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
HTT P42858 1/20 0.42
GAA P10253 1/20 0.42
NR1I2 O75469 1/20 0.41
CYP2C19 P33261 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10923791 0.78 PKM (0.79) LMNAPKMHTR6CYP3A4MPO
Sulfameter SCHEMBL79417 0.76 LMNA (1.00) LMNAHTR6CYP3A4CYP2C9TSHR
Sulfameter SCHEMBL17593237 0.75 LMNA (0.97) LMNAHTR6CYP3A4CYP2C9TSHR
Sulfameter SCHEMBL27709233 0.75 LMNA (0.97) LMNAHTR6CYP3A4CYP2C9TSHR
Sulfameter SCHEMBL11137116 0.75 LMNA (0.97) LMNAHTR6CYP3A4CYP2C9TSHR
SCHEMBL8865655 0.74 TSHR (0.60) LMNAPKMHTR6CYP3A4MPO
SCHEMBL7141365 0.74 HTR6 (0.59) LMNAPKMHTR6CYP3A4MPO
SCHEMBL7266007 0.74 PKM (0.64) LMNAPKMTSHRTDP1MEN1
SCHEMBL20379637 0.73 LMNA (0.53) LMNAPKMHTR6CYP3A4MPO
Sulfanilamide SCHEMBL27668604 0.73 CA2 (0.57) LMNAHTR6TSHRTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103536606-B A kind of wettable sulfamethoxydiazine powder and preparation method thereof CHENGDU QIANKUN ANIMAL PHARMACEUTICAL CO.,LTD. (CN) 2016-03-30 CN disclosed