Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721669 | 0.81 | L3MBTL1 (0.58) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL10267835 | 0.79 | TSHR (0.55) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL8685355 | 0.76 | L3MBTL1 (0.55) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL31668328 | 0.76 | L3MBTL1 (0.55) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL27810549 | 0.75 | L3MBTL1 (0.51) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL1247821 | 0.75 | TSHR (0.54) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL1692172 | 0.74 | TSHR (0.50) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL3923460 | 0.74 | TUBB4A (0.54) | L3MBTL1KMT2AKDM4EALDH1A1CREBBP | |
| SCHEMBL31435498 | 0.74 | TSHR (0.53) | L3MBTL1TSHRRAB9AKMT2AKDM4E | |
| SCHEMBL30681378 | 0.74 | L3MBTL1 (0.43) | L3MBTL1KMT2ACREBBPNOTUMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394923-B | Preparation method of N-acyl-2-alkyl indoline compound | 浙江工业大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-114394923-A | Preparation method of N-acyl-2-alkyl indoline compound | 浙江工业大学 | 2022-04-26 | — | — | CN | disclosed |