Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721996 | 0.85 | HCAR3 (0.56) | PDE5AHCAR3 | |
| SCHEMBL29824742 | 0.81 | ALOX15 (0.74) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL23591998 | 0.81 | ALOX15 (0.74) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL29517779 | 0.81 | ALOX15 (0.55) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL29628982 | 0.78 | ALOX15 (0.49) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL29883452 | 0.75 | ALOX15 (0.51) | ALOX15PTGER4 | |
| SCHEMBL29882859 | 0.74 | ALOX15 (0.47) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL27275947 | 0.73 | ALOX15 (0.61) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL5836935 | 0.72 | ALOX15 (0.70) | ALOX15CHEK1NTRK1METPIM1 | |
| SCHEMBL21311001 | 0.71 | ALOX15 (0.59) | ALOX15PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364664-A | BCAT modulation | 伊卡根有限责任公司 | 2022-04-15 | — | — | CN | disclosed |