Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707706 | 0.88 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPK1TRPV1KMT2A | |
| SCHEMBL28718309 | 0.88 | BRD4 (0.47) | ALDH1A1TRPV1KMT2AMEN1BRD4 | |
| SCHEMBL29670971 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBALOX15MAPK1KMT2A | |
| SCHEMBL28718274 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBALOX15MAPK1KMT2A | |
| SCHEMBL28715966 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10LMNAUSP2 | |
| SCHEMBL28707698 | 0.85 | MAPT (0.54) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL28707700 | 0.85 | GAA (0.48) | KDM4EALDH1A1POLBLMNATRPV1 | |
| SCHEMBL28714011 | 0.84 | BRD4 (0.47) | LMNATRPV1BRD4SMN1; SMN2 | |
| SCHEMBL29670959 | 0.84 | BRD4 (0.47) | LMNATRPV1BRD4SMN1; SMN2 | |
| SCHEMBL28705613 | 0.83 | BRD4 (0.50) | KDM4EALDH1A1HSD17B10TRPV1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |