Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718274 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTPOLBALOX15 | |
| SCHEMBL28707706 | 0.94 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL28718309 | 0.88 | BRD4 (0.47) | ALDH1A1KMT2AMAPTMEN1BRD4 | |
| SCHEMBL28707698 | 0.86 | MAPT (0.54) | ALDH1A1KMT2AMAPTMEN1TP53 | |
| SCHEMBL28722559 | 0.86 | KDM4E (0.53) | ALDH1A1KMT2APOLBALOX15MEN1 | |
| SCHEMBL28715966 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53MAPK1 | |
| SCHEMBL29670965 | 0.84 | BRD4 (0.50) | ALDH1A1MAPTTP53BRD4 | |
| SCHEMBL28705613 | 0.84 | BRD4 (0.50) | ALDH1A1MAPTTP53BRD4 | |
| SCHEMBL28937209 | 0.83 | BRD4 (0.49) | ALDH1A1MAPTBRD4 | |
| SCHEMBL29670961 | 0.83 | BRD4 (0.49) | ALDH1A1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |