Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724713 | 0.91 | PIK3CD (0.42) | PIK3CDCTSDCTSLCTSBCTSS | |
| SCHEMBL28724695 | 0.87 | CTSD (0.33) | CTSDCTSLCTSBCTSSUSP2 | |
| SCHEMBL28724716 | 0.78 | TRPV1 (0.33) | PIK3CDHDAC1NPC1RAB9ALMNA | |
| SCHEMBL12226512 | 0.77 | PIK3CD (0.41) | PIK3CDHDAC1NPC1RAB9ALMNA | |
| SCHEMBL12226514 | 0.77 | PIK3CD (0.41) | PIK3CDHDAC1NPC1RAB9ALMNA | |
| SCHEMBL28724725 | 0.77 | HDAC1 (0.40) | PIK3CDHDAC1NPC1RAB9ALMNA | |
| SCHEMBL28781536 | 0.76 | HSD11B1 (0.40) | PIK3CDCTSDCTSLCTSBCTSS | |
| SCHEMBL28781534 | 0.76 | HSD11B1 (0.40) | PIK3CDCTSDCTSLCTSBCTSS | |
| SCHEMBL13744654 | 0.76 | TDP1 (0.33) | S1PR1SIGMAR1 | |
| SCHEMBL22551842 | 0.76 | EPHX1 (0.42) | GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349748-A | Indazole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2022-04-15 | — | — | CN | disclosed |