Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724715 | 0.91 | PIK3CD (0.33) | PIK3CDUSP2SMN1; SMN2CTSDCTSL | |
| SCHEMBL28724695 | 0.83 | CTSD (0.33) | USP2SMN1; SMN2CTSDCTSLCTSB | |
| SCHEMBL13744654 | 0.82 | TDP1 (0.33) | TDP1L3MBTL1S1PR1CNR2GPR119 | |
| SCHEMBL13209129 | 0.81 | PIK3CD (0.46) | PIK3CDSMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL28724721 | 0.77 | PIK3CD (0.39) | PIK3CDTDP1L3MBTL1HSD11B1 | |
| SCHEMBL18772659 | 0.77 | SIGMAR1 (0.35) | USP2SMN1; SMN2CTSDCTSLCTSB | |
| SCHEMBL13209127 | 0.75 | PIK3CD (0.50) | PIK3CDKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL12226508 | 0.75 | PIK3CD (0.50) | PIK3CDKDM4EALDH1A1POLBS1PR1 | |
| SCHEMBL24951478 | 0.75 | EPHX1 (0.44) | PIK3CDCTSDCTSLCTSBCTSS | |
| SCHEMBL4314784 | 0.75 | SLC6A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349748-A | Indazole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2022-04-15 | — | — | CN | disclosed |