Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444856 | 0.88 | L3MBTL1 (0.43) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL13365015 | 0.81 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL28724882 | 0.78 | ALDH1A1 (0.41) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11900091 | 0.76 | ALDH1A1 (0.42) | LMNAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL13365021 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL5333776 | 0.76 | RXFP1 (0.48) | LMNAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28724752 | 0.76 | KDM4E (0.44) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL5317707 | 0.75 | NPSR1 (0.48) | LMNAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2362194 | 0.75 | KDM4E (0.41) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL27243156 | 0.74 | KMT2A (0.43) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349703-B | Trifluoromethyl-4-cyano pyrazole compound, and preparation method and application thereof | 天津大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-114349703-A | Trifluoromethyl-4-cyanopyrazole compound, and preparation method and application thereof | 天津大学 | 2022-04-15 | — | — | CN | disclosed |