Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317707 | 0.80 | NPSR1 (0.48) | RXFP1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28724747 | 0.76 | LMNA (0.43) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL28724882 | 0.69 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5340378 | 0.68 | LMNA (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL630534 | 0.67 | ALDH1A1 (0.48) | MAPTALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL13184169 | 0.67 | LMNA (0.55) | MAPTALDH1A1KMT2APOLBL3MBTL1 | |
| SCHEMBL22381039 | 0.66 | SMN1; SMN2 (0.47) | MAPTALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28724752 | 0.66 | KDM4E (0.44) | MAPTALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14385592 | 0.66 | RXFP1 (1.00) | RXFP1MAPTTHRBALDH1A1HPGD | |
| SCHEMBL4625127 | 0.65 | LMNA (0.54) | MAPTALDH1A1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084868-A2 | TREATMENT OF DISORDERS BY ACTIVATION OF THE UNFOLDED PROTEIN RESPONSE | KALYPSYS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |