Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724765 | 0.86 | KIF11 (0.46) | KIF11 | |
| SCHEMBL28724743 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EGAAADORA1MEN1 | |
| SCHEMBL28724777 | 0.86 | MAPT (0.41) | GRM5ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28724773 | 0.86 | KIF11 (0.46) | ALDH1A1KDM4EADORA1MEN1KMT2A | |
| SCHEMBL28724767 | 0.85 | GAA (0.44) | ALDH1A1GAAHPGDGLAADORA1 | |
| SCHEMBL28724776 | 0.85 | GRM5 (0.44) | GRM5ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28724804 | 0.83 | MAPT (0.43) | GRM5ALDH1A1HPGDADORA1MEN1 | |
| SCHEMBL28724772 | 0.82 | DHODH (0.43) | ALDH1A1KDM4EHPGDKMT2ATDP1 | |
| SCHEMBL28724967 | 0.81 | MAPT (0.47) | ALDH1A1KDM4EHPGDGLAADORA1 | |
| SCHEMBL28724758 | 0.80 | GRM5 (0.50) | GRM5ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349703-B | Trifluoromethyl-4-cyano pyrazole compound, and preparation method and application thereof | 天津大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-114349703-A | Trifluoromethyl-4-cyanopyrazole compound, and preparation method and application thereof | 天津大学 | 2022-04-15 | — | — | CN | disclosed |