Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 8/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405393 | 0.82 | DHODH (0.63) | SLC6A3DHODH | |
| SCHEMBL2222523 | 0.72 | GABRA5 (0.52) | SLC6A3SLC6A2GABRA5 | |
| SCHEMBL468420 | 0.72 | DHODH (0.80) | DHODH | |
| SCHEMBL2405740 | 0.68 | DHODH (0.83) | DHODH | |
| SCHEMBL18668155 | 0.67 | MEN1 (0.50) | SLC6A3SLC6A2 | |
| SCHEMBL2848357 | 0.67 | DHODH (0.62) | DHODH | |
| SCHEMBL2127961 | 0.65 | DHODH (0.68) | DHODH | |
| SCHEMBL3724535 | 0.65 | OPRK1 (0.47) | SLC6A3DHODH | |
| SCHEMBL14152801 | 0.65 | CNR2 (0.64) | SLC6A3CNR2SLC6A2CNR1 | |
| SCHEMBL3576543 | 0.65 | SLC6A3 (0.46) | SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |