Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287585 | 0.74 | NPSR1 (0.46) | TDP1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL287683 | 0.73 | NPC1 (0.39) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL287467 | 0.71 | POLB (0.36) | LMNANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL137486 | 0.70 | TDP1 (0.83) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| Cyclopropane SCHEMBL5387563 | 0.68 | TDP1 (0.73) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL28286830 | 0.68 | TDP1 (0.79) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL16217656 | 0.68 | TDP1 (0.79) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL547137 | 0.68 | TDP1 (0.79) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL13292516 | 0.68 | TDP1 (0.79) | TDP1LMNANPC1RAB9AL3MBTL1 | |
| Ethylene SCHEMBL8622525 | 0.67 | TDP1 (0.76) | TDP1LMNANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |