Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287807 | 0.82 | ALDH1A1 (0.38) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL287785 | 0.79 | SMN1; SMN2 (0.41) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL287282 | 0.74 | TDP1 (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL287728 | 0.69 | NPSR1 (0.46) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL13100724 | 0.69 | HPGD (0.74) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL6227338 | 0.68 | NPSR1 (0.60) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL1194141 | 0.68 | NPSR1 (0.58) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL1194544 | 0.66 | HSP90AA1 (0.61) | NPSR1ALDH1A1HPGD | |
| SCHEMBL18972439 | 0.65 | POLB (0.71) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL7603207 | 0.65 | TDP1 (0.63) | NPSR1SMN1; SMN2ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |