Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287683 | 0.86 | NPC1 (0.39) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL287370 | 0.79 | ALDH1A1 (0.43) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL287825 | 0.71 | ALDH1A1 (0.34) | CYP1A2CYP2D6RAB9AHPGDNPC1 | |
| SCHEMBL287282 | 0.71 | TDP1 (0.43) | RAB9AHPGDNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL287968 | 0.71 | TDP1 (0.41) | CYP2C19RAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL285705 | 0.70 | ALDH1A1 (0.33) | POLBCYP1A2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL287119 | 0.69 | ALDH1A1 (0.39) | POLBCYP1A2CYP2D6RAB9AHPGD | |
| SCHEMBL660574 | 0.69 | ALDH1A1 (0.38) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL287432 | 0.66 | TSHR (0.41) | POLBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL471019 | 0.64 | ALDH1A1 (0.69) | POLBCYP1A2CYP2D6RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |