Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808799 | 0.95 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL2004098 | 0.80 | CHRNB2 (0.54) | CHRNB2CHRNA4MAPTRAB9ANPSR1 | |
| Formaldehyde SCHEMBL28138949 | 0.77 | GSTP1 (0.52) | CA12CA1CA2CA4CA7 | |
| SCHEMBL4810770 | 0.77 | CYP19A1 (0.60) | RAB9A | |
| SCHEMBL105590 | 0.77 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL7305175 | 0.77 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL28393152 | 0.75 | MAPK1 (0.53) | — | |
| SCHEMBL2005120 | 0.74 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL11478353 | 0.74 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL601439 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409716-B | Sugar-modified metal helix complex, preparation method thereof and application thereof as amyloid degradation device | 中国科学院长春应用化学研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-114409716-B | Sugar-modified metal helix complex, preparation method thereof and application thereof as amyloid degradation device | 中国科学院长春应用化学研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-114409716-A | Sugar-modified metal helix complex, preparation method thereof and application of complex as amyloid degradation device | 中国科学院长春应用化学研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409716-A | Sugar-modified metal helix complex, preparation method thereof and application of complex as amyloid degradation device | 中国科学院长春应用化学研究所 | 2022-04-29 | — | — | CN | disclosed |