Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 16/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731887 | 0.86 | ROCK2 (0.50) | ROCK2ROCK1AKT1AKT2 | |
| SCHEMBL36018 | 0.82 | TTR (0.62) | — | |
| SCHEMBL29043855 | 0.81 | ROCK2 (0.53) | ROCK2ROCK1 | |
| SCHEMBL15995837 | 0.81 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL30461965 | 0.81 | ROCK2 (0.53) | ROCK2ROCK1 | |
| SCHEMBL31482437 | 0.80 | AKT2 (0.63) | ROCK2ROCK1AKT1AKT2 | |
| SCHEMBL3809545 | 0.79 | TTR (0.58) | — | |
| SCHEMBL2213544 | 0.79 | TTR (0.58) | — | |
| SCHEMBL8149892 | 0.79 | PTPRC (0.66) | — | |
| SCHEMBL28552255 | 0.79 | AKT2 (0.72) | ROCK2AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620878-B | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2023-01-31 | — | — | CN | claimed |
| CN-113620878-A | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2021-11-09 | — | — | CN | claimed |
| CN-115007212-B | Integrated metal organic framework based CO 2 Photo-thermal catalyst and preparation method and application thereof | 浙江大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-113620878-B | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113620878-B | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115007212-A | Integrated metal-organic framework-based CO 2 Photo-thermal catalyst and preparation method and application thereof | 浙江大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-113620878-A | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-113620878-A | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2021-11-09 | — | — | CN | disclosed |