Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690763 | 1.00 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL15985646 | 1.00 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| Hydrochloric Acid SCHEMBL29063300 | 0.99 | CTSL (0.44) | CTSLCTSBCAPN1 | |
| Hydrochloric Acid SCHEMBL29609436 | 0.99 | CTSL (0.44) | CTSLCTSBCAPN1 | |
| Hydrochloric Acid SCHEMBL29063299 | 0.99 | CTSL (0.44) | CTSLCTSBCAPN1 | |
| SCHEMBL19605950 | 0.93 | CTSB (0.43) | CTSLCTSB | |
| SCHEMBL24828173 | 0.89 | CTSL (0.41) | CTSLCTSBCAPN1 | |
| SCHEMBL23824248 | 0.88 | CTSL (0.43) | CTSLCTSBCAPN1 | |
| SCHEMBL24109107 | 0.88 | CTSL (0.42) | CTSLCTSBCAPN1 | |
| SCHEMBL24486589 | 0.88 | CTSL (0.42) | CTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114681443-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2024-05-10 | — | — | CN | disclosed |
| CN-116789648-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-09-22 | — | — | CN | disclosed |
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114466838-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-05-02 | — | — | CN | disclosed |
| CN-114681443-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-07-01 | — | — | CN | disclosed |
| CN-114466838-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-05-10 | — | — | CN | disclosed |