Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690763 | 0.89 | CTSL (0.45) | CTSLCAPN1CTSB | |
| SCHEMBL15985646 | 0.89 | CTSL (0.45) | CTSLCAPN1CTSB | |
| SCHEMBL28732875 | 0.89 | CTSL (0.45) | CTSLCAPN1CTSB | |
| SCHEMBL24425334 | 0.89 | CTSL (0.38) | CTSLCAPN1CTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL29063299 | 0.88 | CTSL (0.44) | CTSLCAPN1CTSB | |
| Hydrochloric Acid SCHEMBL29609436 | 0.88 | CTSL (0.44) | CTSLCAPN1CTSB | |
| Hydrochloric Acid SCHEMBL29063300 | 0.88 | CTSL (0.44) | CTSLCAPN1CTSB | |
| SCHEMBL19605950 | 0.83 | CTSB (0.43) | CTSLCTSBCTSS | |
| SCHEMBL23506394 | 0.82 | CTSL (0.33) | CTSLCAPN1CTSB | |
| SCHEMBL24530155 | 0.82 | CTSL (0.33) | CTSLCAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | PFIZER INC. (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | ACE2, NOS2, EIF2AK2 | CTSL 635/4885CAPN1 1185/4885CTSB 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.