Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291658 | 0.90 | TP53 (0.67) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL25916294 | 0.83 | HPGD (0.78) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL30362646 | 0.83 | HPGD (0.78) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL9042466 | 0.80 | KDM4E (0.81) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL2740138 | 0.80 | ALDH1A1 (0.60) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL25916299 | 0.80 | TP53 (0.64) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL31277445 | 0.80 | MMP2 (0.71) | HPGDALDH1A1TP53TDP1MAPT | |
| SCHEMBL30211772 | 0.80 | TP53 (0.64) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL12963277 | 0.79 | HPGD (0.69) | HPGDALDH1A1TP53TDP1TSHR | |
| SCHEMBL12963282 | 0.79 | HPGD (0.68) | HPGDALDH1A1TP53TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971465-B | Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof | 渤海大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-109971465-B | Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof | 渤海大学 | 2022-03-18 | — | — | CN | disclosed |