⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258447 | 0.85 | TSHR (0.43) | — | |
| SCHEMBL214978 | 0.80 | — | — | |
| SCHEMBL31426278 | 0.80 | DGKA (0.43) | — | |
| SCHEMBL5902744 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL22467688 | 0.76 | GAA (0.50) | — | |
| SCHEMBL3447386 | 0.76 | EGLN1 (0.46) | — | |
| SCHEMBL445303 | 0.76 | CES1 (0.46) | — | |
| SCHEMBL279949 | 0.75 | — | — | |
| SCHEMBL19767587 | 0.74 | TSHR (0.44) | — | |
| SCHEMBL8903601 | 0.74 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114522155-B | Lidocaine percutaneous absorption pharmaceutical composition and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-114522155-A | Lidocaine percutaneous absorption pharmaceutical composition and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2022-05-24 | — | — | CN | disclosed |