SCHEMBL28735781

SCHEMBL28735781

CCCCOC(=O)CCN(CCC)CCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
DNM1 Q05193 1/20 0.51
NAAA Q02083 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HTR2C P28335 1/20 0.46
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
ATM Q13315 1/20 0.44
FAAH O00519 1/20 0.43
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
RAD52 P43351 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPK1 P28482 1/20 0.40
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12120249 0.96 DGKA (0.55) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL15015609 0.94 DGKA (0.53) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL2006674 0.94 DGKA (0.53) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL12120086 0.92 DGKA (0.52) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL12120248 0.90 NAAA (0.59) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL21512458 0.89 DNM1 (0.49) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL10762985 0.89 DGKA (0.52) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL12120251 0.89 NAAA (0.62) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL12120250 0.89 NAAA (0.62) DGKADNM1NAAAALDH1A1HTR2C
SCHEMBL889158 0.88 DNM1 (0.46) DGKADNM1NAAAALDH1A1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN claimed
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN disclosed