Anisole

Anisole

SCHEMBL2873709

COc1ccccc1.Cc1cccc(Oc2ccccc2)c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.69
LTA4H P09960 2/20 0.65
ALDH1A1 P00352 6/20 0.61
CA4 P22748 1/20 0.56
GAA P10253 3/20 0.53
HTT P42858 4/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
AR P10275 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPK1 P28482 1/20 0.49
GFER P55789 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RELA Q04206 1/20 0.49
MAOB P27338 2/20 0.48
TSHR P16473 1/20 0.48
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358265 0.94 ACHE (0.72) ACHELTA4HALDH1A1GAAHTT
SCHEMBL3294529 0.94 ACHE (0.72) ACHELTA4HALDH1A1GAAHTT
Diphenylether SCHEMBL10909478 0.92 ALDH1A1 (0.70) ACHELTA4HALDH1A1GAAHTT
SCHEMBL441890 0.92 ALDH1A1 (0.70) ACHELTA4HALDH1A1GAAHTT
Hydrochloric Acid SCHEMBL28556055 0.90 ALDH1A1 (0.68) ACHELTA4HALDH1A1GAAHTT
Bromide SCHEMBL10786627 0.90 ALDH1A1 (0.68) ACHELTA4HALDH1A1GAAHTT
Bromide SCHEMBL10791123 0.90 ALDH1A1 (0.68) ACHELTA4HALDH1A1GAAHTT
Hydrochloric Acid SCHEMBL11153798 0.90 ALDH1A1 (0.68) ACHELTA4HALDH1A1GAAHTT
SCHEMBL19341802 0.90 ALDH1A1 (0.68) ACHELTA4HALDH1A1GAAHTT
Anisole SCHEMBL28301167 0.90 ACHE (0.86) ACHELTA4HALDH1A1CA4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10497875-B2 Hole transporting cyclobutene compound CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-12-03 US disclosed
US-20170207394-A1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
WO-2010079331-A1 INTERLAYER FORMULATION FOR FLAT FILMS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-07-15 WO disclosed
WO-2010079330-A1 INTERLAYER FORMULATION FOR FLAT FILMS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10497875-B2 Hole transporting cyclobutene compound SP1, NR0B1, CCNT1 ACHE 4684/4885LTA4H 3303/4885ALDH1A1 1559/4885
US-20170207394-A1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND SP1, NR0B1, CCNT1 ACHE 4684/4885LTA4H 3303/4885ALDH1A1 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.