SCHEMBL19341802

SCHEMBL19341802

Cc1cccc(Oc2cccc(Oc3ccccc3)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
GAA P10253 2/20 0.58
ACHE P22303 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
HTT P42858 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
LTA4H P09960 2/20 0.55
TSHR P16473 1/20 0.55
MAOB P27338 1/20 0.54
GFER P55789 2/20 0.53
MAPK1 P28482 1/20 0.53
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL10909478 0.98 ALDH1A1 (0.70) ALDH1A1GAAACHEL3MBTL1HTT
SCHEMBL441890 0.98 ALDH1A1 (0.70) ALDH1A1GAAACHEL3MBTL1HTT
Fluoride SCHEMBL27390732 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
Water SCHEMBL27786743 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
Hydrochloric Acid SCHEMBL28556055 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
Bromide SCHEMBL10791123 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
Hydrochloric Acid SCHEMBL11153798 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
Bromide SCHEMBL10786627 0.95 ALDH1A1 (0.68) ALDH1A1GAAACHEL3MBTL1HTT
SCHEMBL1688852 0.93 ALDH1A1 (0.69) ALDH1A1GAAACHEL3MBTL1HTT
SCHEMBL14159539 0.91 ALDH1A1 (0.80) ALDH1A1GAAACHEL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-10457780-B2 Hygromorphic polymers and copolymers having humidity-driven motility UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-10-29 US disclosed
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-07-12 US disclosed
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-07-12 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-02-08 US disclosed
US-20170260334-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2017-09-14 US disclosed
US-20170260334-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 ALDH1A1 2119/4885GAA 1702/4885ACHE 3388/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR ALDH1A1 2965/4885GAA 2185/4885ACHE 3716/4885
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY DNAH12, PARG, PARN ALDH1A1 2805/4885GAA 2073/4885ACHE 3314/4885
US-10457780-B2 Hygromorphic polymers and copolymers having humidity-driven motility DNAH12, PARG, PARN ALDH1A1 2805/4885GAA 2073/4885ACHE 3314/4885
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION C9, TYR, CCNA1 ALDH1A1 990/4885GAA 3758/4885ACHE 4662/4885
US-20170260334-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY DNAH12, PARG, PARN ALDH1A1 2805/4885GAA 2073/4885ACHE 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.