SCHEMBL287397

SCHEMBL287397

CC1(C)C[C]CC(C)(C)N1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3133473 0.68
SCHEMBL243842 0.68
SCHEMBL887146 0.65
SCHEMBL21189243 0.65 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2
SCHEMBL15516050 0.63
SCHEMBL4071694 0.62 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2
SCHEMBL1928918 0.62 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL15100 0.59 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL34473678 0.59 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL677357 0.59 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4102858-A LIGHT STABILIZERS FOR PVC AND POLYAMIDES ARGUS CHEMICAL CORPORATION (US) 1978-07-25 US claimed
US-9127098-B2 O-imino-iso-urea compounds and polymerizable compositions thereof BASF SE (DE) 2015-09-08 US disclosed
EP-2427428-B1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2015-08-19 EP disclosed
US-20140113987-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2014-04-24 US disclosed
US-8664288-B2 O-imino-iso-urea compounds and polymerizable compositions thereof BASF SE (DE) 2014-03-04 US disclosed
US-20120108696-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2012-05-03 US disclosed
EP-2427428-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2012-03-14 EP disclosed
WO-2010128062-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2010-11-11 WO disclosed
EP-0107805-B1 MIXED 2,2,6,6-TETRAMETHYL PIPERIDINYL CARBOXYLIC ACID ESTER AND AMIDE LIGHT STABILIZERS AND STABILIZED SYNTHETIC POLYMERS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1989-12-13 EP disclosed
EP-0108993-B1 OLIGOMERS OF 2,2,6,6-TETRAMETHYLPIPERIDINOL, POLYCARBOXYLIC ACID ESTERS AND SYNTHETIC POLYMER COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1986-12-17 EP disclosed
US-4619958-A Mixed 2,2,6,6-tetramethyl piperidinyl carboxylic acid ester and amide light stabilizers and stabilized synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1986-10-28 US disclosed
US-4529760-A Oligomers of 2,2,6,6-tetramethylpiperidinol polycarboxylic acid esters and synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1985-07-16 US disclosed
EP-0108993-A1 Oligomers of 2,2,6,6-tetramethylpiperidinol, polycarboxylic acid esters and synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-05-23 EP disclosed
EP-0107805-A2 Mixed 2,2,6,6-tetramethyl piperidinyl carboxylic acid ester and amide light stabilizers and stabilized synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-05-09 EP disclosed
US-4102858-A LIGHT STABILIZERS FOR PVC AND POLYAMIDES ARGUS CHEMICAL CORPORATION (US) 1978-07-25 US disclosed
US-4102858-A LIGHT STABILIZERS FOR PVC AND POLYAMIDES ARGUS CHEMICAL CORPORATION (US) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108696-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF CCNC, CCNO, CCNI ALDH1A1 1464/4885SMN1; SMN2 2641/4885
US-20140113987-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF CCNC, CPS1, ODC1 ALDH1A1 1257/4885SMN1; SMN2 3307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.