Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287275 | 0.90 | GSK3B (0.36) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287518 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL286928 | 0.78 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL285705 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL287118 | 0.74 | KMT2A (0.33) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287292 | 0.73 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287274 | 0.72 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL286738 | 0.72 | KMT2A (0.38) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287196 | 0.71 | HSD17B10 (0.41) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287307 | 0.70 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |