Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287825 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287278 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL287418 | 0.75 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287307 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287370 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287408 | 0.70 | RAB9A (0.43) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL287467 | 0.70 | POLB (0.36) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287683 | 0.68 | NPC1 (0.39) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL287968 | 0.67 | TDP1 (0.41) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL287275 | 0.66 | GSK3B (0.36) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |