Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851931 | 0.76 | MAPT (0.40) | KDM4EALDH1A1 | |
| SCHEMBL29626809 | 0.74 | HSD17B10 (0.38) | FABP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL31092008 | 0.70 | HSP90AA1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL28741778 | 0.69 | GRM4 (0.33) | NT5E | |
| SCHEMBL3631708 | 0.67 | ENPP1 (0.56) | NT5EKDM4EALDH1A1 | |
| SCHEMBL30911387 | 0.66 | NT5E (0.34) | NT5E | |
| SCHEMBL30911391 | 0.66 | NT5E (0.34) | NT5EALDH1A1 | |
| SCHEMBL35210853 | 0.66 | NT5E (0.33) | NT5E | |
| SCHEMBL10850431 | 0.66 | NT5E (0.42) | NT5EFABP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3465338 | 0.65 | DAO (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |