Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 5/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626809 | 0.85 | HSD17B10 (0.38) | ALDH1A1MAPTADRB2KDM4EHPGD | |
| SCHEMBL29626563 | 0.74 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1HTR6ATRATRIP | |
| SCHEMBL28741889 | 0.70 | NT5E (0.44) | ALDH1A1KDM4E | |
| SCHEMBL31091993 | 0.69 | DHODH (0.34) | CNR2 | |
| SCHEMBL22944911 | 0.68 | CBLB (0.36) | IDH2KDM4EHPGDMAPK1 | |
| SCHEMBL1285165 | 0.64 | ADRB2 (0.50) | ALDH1A1MEN1MAPTKMT2AADRB2 | |
| SCHEMBL31091998 | 0.63 | ADRB2 (0.37) | MEN1MAPTKMT2AIDH2ADRB2 | |
| SCHEMBL25246123 | 0.59 | HRH4 (0.43) | IDH2 | |
| SCHEMBL21212248 | 0.59 | CBLB (0.41) | HSP90AA1HSP90AB1ALDH1A1MEN1MAPT | |
| SCHEMBL30455420 | 0.59 | HRH4 (0.43) | IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |