Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28741843 | 0.98 | DGAT1 (0.39) | DGAT1KDM4EKMT2A | |
| SCHEMBL1682674 | 0.79 | DGAT1 (0.36) | DGAT1KDM4EKMT2A | |
| SCHEMBL12539658 | 0.78 | DGAT1 (0.61) | DGAT1KMT2A | |
| Hydrochloric Acid SCHEMBL1281965 | 0.77 | DGAT1 (0.35) | DGAT1KDM4EKMT2A | |
| SCHEMBL1282458 | 0.77 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL30805343 | 0.77 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL13897319 | 0.75 | DGAT1 (0.52) | DGAT1KMT2A | |
| SCHEMBL21661359 | 0.73 | KDM4E (0.38) | KDM4EKMT2A | |
| Trifluoroacetic Acid SCHEMBL31026676 | 0.70 | PKM (0.30) | — | |
| SCHEMBL13990474 | 0.69 | KDM4E (0.38) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| EP-4003965-A1 | UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION | Nurix Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |