Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.59 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640453 | 1.00 | SIGMAR1 (0.59) | SIGMAR1SLC6A12POLB | |
| SCHEMBL22966087 | 0.82 | SIGMAR1 (0.62) | SIGMAR1POLB | |
| SCHEMBL28741993 | 0.79 | SIGMAR1 (0.77) | SIGMAR1POLB | |
| SCHEMBL2821246 | 0.78 | ACHE (0.73) | SIGMAR1SLC6A12 | |
| SCHEMBL6333442 | 0.77 | SIGMAR1 (0.73) | SIGMAR1POLB | |
| SCHEMBL4848450 | 0.77 | SIGMAR1 (0.77) | SIGMAR1POLB | |
| SCHEMBL22966100 | 0.76 | OPRM1 (0.41) | SIGMAR1SLC6A12 | |
| SCHEMBL13360982 | 0.76 | SIGMAR1 (0.75) | SIGMAR1POLB | |
| SCHEMBL9852459 | 0.76 | SIGMAR1 (0.75) | SIGMAR1POLB | |
| SCHEMBL5862113 | 0.75 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |