Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381854 | 0.84 | HTT (0.50) | POLBHTTNPSR1L3MBTL1CTSD | |
| SCHEMBL8770864 | 0.84 | POLB (0.47) | POLBHTTNPSR1L3MBTL1MTNR1A | |
| SCHEMBL4392054 | 0.83 | ADRA1A (0.40) | MTNR1AMTNR1BLMNACYP1A2 | |
| SCHEMBL21656592 | 0.83 | POLB (0.50) | POLBHTTNPSR1L3MBTL1MTNR1A | |
| Hydrochloric Acid SCHEMBL6704501 | 0.82 | MEN1 (0.41) | MTNR1AMTNR1BLMNACYP1A2 | |
| SCHEMBL7837944 | 0.80 | ALDH1A1 (0.34) | POLBHTTNPSR1L3MBTL1MTNR1A | |
| SCHEMBL5720914 | 0.80 | POLB (0.55) | POLBHTTNPSR1L3MBTL1CTSD | |
| SCHEMBL3385975 | 0.80 | POLB (0.55) | POLBHTTNPSR1L3MBTL1CTSD | |
| SCHEMBL12463681 | 0.80 | POLB (0.55) | POLBHTTNPSR1L3MBTL1CTSD | |
| SCHEMBL31364568 | 0.80 | POLB (0.55) | POLBHTTNPSR1L3MBTL1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1221535-C | Spiroimidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMA GMBH (DE) | 2005-10-05 | — | — | CN | disclosed |
| CN-1356986-A | Spiroimidazolidine derivatives, their prepn. their use and pharmaceutical prepns. comprising them | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | CN | disclosed |