Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849511 | 0.81 | TLR8 (0.57) | SOD1TSHRQPCT | |
| SCHEMBL6470178 | 0.74 | TLR8 (0.51) | — | |
| SCHEMBL7081073 | 0.73 | TLR8 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7081070 | 0.73 | TLR8 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11247886 | 0.71 | POLB (0.68) | SOD1KMT2AQPCTLMNA | |
| SCHEMBL28623269 | 0.71 | CYP19A1 (0.55) | — | |
| SCHEMBL10919184 | 0.70 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL28742405 | 0.69 | CYP19A1 (0.68) | SOD1 | |
| SCHEMBL24852090 | 0.69 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL24853011 | 0.69 | TLR8 (0.45) | KMT2AMEN1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1251577-A | Fused ring compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | CN | disclosed |