Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341280 | 0.86 | HDAC1 (0.81) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL28742702 | 0.86 | HDAC1 (0.81) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL6698550 | 0.84 | MAPT (0.65) | MAPTGAAL3MBTL1 | |
| SCHEMBL17086799 | 0.80 | HDAC1 (0.54) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL5577580 | 0.80 | MAPT (0.62) | MAPT | |
| SCHEMBL29799167 | 0.80 | HDAC1 (0.65) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL28742970 | 0.80 | HDAC1 (0.65) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL18108986 | 0.80 | HDAC1 (0.52) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17704541 | 0.79 | ALDH1A1 (0.61) | MAPTGAAL3MBTL1PRKAA2 | |
| SCHEMBL5544112 | 0.79 | MAPT (0.74) | MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539130-B | Phenylpiperazine or phenylpiperidine compounds and application thereof | 温州医科大学 | 2023-08-11 | — | — | CN | claimed |
| CN-114539130-A | Phenyl piperazine or phenyl piperidine compound and application thereof | 温州医科大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114539130-B | Phenylpiperazine or phenylpiperidine compounds and application thereof | 温州医科大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114539130-A | Phenyl piperazine or phenyl piperidine compound and application thereof | 温州医科大学 | 2022-05-27 | — | — | CN | disclosed |