Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799167 | 1.00 | HDAC1 (0.65) | HDAC1HDAC4KCNH2SMN1; SMN2HDAC6 | |
| SCHEMBL28742702 | 0.87 | HDAC1 (0.81) | HDAC1HDAC4KCNH2SMN1; SMN2HDAC6 | |
| SCHEMBL6030721 | 0.82 | KDM4E (0.72) | KCNH2SMN1; SMN2HTR1AHTR7USP2 | |
| SCHEMBL12341280 | 0.82 | HDAC1 (0.81) | HDAC1HDAC4KCNH2SMN1; SMN2HDAC6 | |
| SCHEMBL18177888 | 0.81 | DRD2 (0.65) | KCNH2SMN1; SMN2HTR1AHTR7USP2 | |
| Bromide SCHEMBL6575201 | 0.81 | KDM4E (0.70) | KCNH2SMN1; SMN2HTR1AHTR7USP2 | |
| SCHEMBL18690249 | 0.80 | HDAC1 (0.76) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL9374413 | 0.80 | SIGMAR1 (0.76) | KCNH2HTR1AHTR7USP2LMNA | |
| SCHEMBL28742676 | 0.80 | HDAC1 (0.64) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL18690263 | 0.79 | HDAC1 (0.74) | HDAC1HDAC4KCNH2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539130-B | Phenylpiperazine or phenylpiperidine compounds and application thereof | 温州医科大学 | 2023-08-11 | — | — | CN | claimed |
| CN-114539130-A | Phenyl piperazine or phenyl piperidine compound and application thereof | 温州医科大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114539130-B | Phenylpiperazine or phenylpiperidine compounds and application thereof | 温州医科大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114539130-A | Phenyl piperazine or phenyl piperidine compound and application thereof | 温州医科大学 | 2022-05-27 | — | — | CN | disclosed |